Jeff completed his MD/PhD at the University of Pennsylvania, did residency at Children's Hospital of Philadelphia, and moved to Boston Children’s Hospital at Harvard Medical School for his fellowship in Pediatric Infectious Diseases. After finishing his clinical fellowship, he completed a postdoctoral fellowship in the laboratory of Manoj Duraisingh in the Department of Immunology and Infectious Diseases at the Harvard School of Public Health to study the molecular pathogenesis of the human malaria parasite Plasmodium falciparum. He joined the faculty at Boston Children's Hospital and Harvard Medical School in 2010, and started his independent laboratory in 2011. Since starting his laboratory, Jeff has continued to apply novel techniques to understand the critical cell biology of the Plasmodium falciparum parasite. In addition, Jeff continues to be clinically active in the Division of Infectious Diseases at the hospital.