2023
Cepeda Diaz AK, Rudlaff RM, Farringer, Dvorin JD. Essential function of alveolin PfIMC1g in the Plasmodium falciparum asexual blood stage. mBio (2023).
Morano AA, Rudlaff RM, Dvorin JD. A PPP-type pseudophosphatase is required for the maintenance of basal complex integrity in Plasmodium falciparum. Nature Communications (2023).
Chawla J, Goldowitz I, Oberstaller J, Zhang M, Pires CV, Navarro F, Sollelis L, Wang CCQ, Seyfang A, Dvorin JD, Otto TD, Rayner JC, Marti M, Adams JH. Phenotypic Screens Identify Genetic Factors Associated with Gametocyte Development in the Human Malaria Parasite Plasmodium falciparum. Microbiology Spectrum (2023).
Liffner B, Cepeda Diaz AK, Blauwkamp J, Anaguano D, Frölich S, Muralidharan V, Wilson DW, Dvorin JD, Absalon S. Atlas of Plasmodium falciparum intraerythrocytic development using expansion microscopy. eLife (2023).
2022
Clements RL, Morano AA, Navarro FM, McGee JP, Du EW, Streva VA, Lindner SE, Dvorin JD. Identification of a basal complex protein that is essential for maturation of transmission-stage malaria parasites. PNAS (2022).
Dvorin JD, Goldberg DE. Plasmodium Egress Across the Parasite Life Cycle. Annual Review of Microbiology (2022).
2021
Moran CJ, Dvorin JD. The Basal Complex Protein PfMORN1 is not required for asexual replication of Plasmodium falciparum. mSphere (2021)
Morano A, Dvorin JD. The Ringleaders: Understanding the Apicomplexan Basal Complex Through Comparison to Established Contractile Ring Systems. Frontiers in Cellular and Infection Microbiology (2021)
Absalon S, Dvorin JD. Depletion of Mini-Chromosome Maintenance Complex Binding Protein allows the progression of cytokinesis despite abnormal karyokinesis during the asexual development of Plasmodium falciparum. Cellular Microbiology (2021)
Junqueira C, Polidoro R, Castro G, Absalon S, Liang Z, Sentara S, Crespo A, Pereira, Dvorin JD, Lieberman J. γδ T cells suppress Plasmodium falciparum blood stage infection by direct killing and phagocytosis. Nature Immunology 2021
Davidson MS, Andradi-Brown C, Yahiya S, Chmielewski J, O'Donnell AJ, Gurung P, Jeninga MD, Prommana P, Andrew DW, Petter M, Uthaipibull C, Boyle MJ, Ashdown GW, Dvorin JD, Reece SE, Wilson DW, Cunningham KA, Ando DM, Dimon M, Baum J. Automated detection and staging of malaria parasites from cytological smears using convolutional neural networks. Biological Imaging (2021).
2020
Lee RA, De Puig H, Nguyen PQ, Angenent-Mari NM, Donghia NM, McGee JP, Dvorin JD, Klapperich CM, Pollock NR, Collins JJ. Ultrasensitive CRISPR-based diagnostic for field-applicable detection of Plasmodium species in symptomatic and asymptomatic malaria. PNAS (2020)
Rudlaff RM, Kraemer S, Marshman J, Dvorin JD. Three-dimensional ultrastructure of Plasmodium falciparum throughout cytokinesis. PLOS Pathogens (2020)
Raj DK, Mohaptra AD, Jnawali A, Zuromski J, Jha A, Cham-Kpu G, Sherman B, Rudlaff RM, Nixon CE, Hilton N, Oleinikov AV, Chesnokov O, Merritt J, Pond-Tor S, Burns L, Jolly G, Ben Mamoun C, Kabyemela E, Meuhlenbachs A, Lambert L, Orr-Gonzalez S, Gnadig NF, Fidock DA, Park S, Dvorin JD, Pardi N, Weissman D, Mui BL, Tam YK, Friedman JF, Fried M, Duffy PE, Kurtis JD. Anti-PfGARP activates programmed cell death of parasites and reduces severe malaria. Nature (2020)
Blomqvist K, Helmel M, Wang C, Absalon S, Labunska T, Rudlaff RM, Adapa S, Jiang R, Steen H, Dvorin JD. Influence of Plasmodium falciparum Calcium-Dependent Protein Kinase 5 (PfCDPK5) on the Late Schizont Stage Phosphoproteome. mSphere 5(1): e00921-19.
Clements RL, Streva V, Dumoulin P, Huang W, Owens E, Raj DK, Burleigh B, Llinás M, Winzeler EA, Zhang Q, Dvorin JD. A novel antiparasitic compound kills ring-stage Plasmodium falciparum and retains activity against artemisinin-resistant parasites. The Journal of Infectious Diseases (2020)
2019
Rudlaff RM, Kraemer S, Streva VA, Dvorin JD. An essential contractile ring protein controls cell division in Plasmodium falciparum. Nature Communications (2019) 10: 2181.
2018
Absalon S, Blomqvist K, Rudlaff RM, DeLano TJ, Pollastri MP, Dvorin JD. Calcium-Dependent Protein Kinase 5 is Required for Release of Egress-Specific Organelles in Plasmodium falciparum. mBio; 9(1): e00130-10.
2017
Robbins, JA, Absalon S, Streva VA, Dvorin JD. The Malaria Parasite Cyclin H Homolog PfCyc1 Is Required for Efficient Cytokinesis in Blood-Stage Plasmodium falciparum. mBio; 8(3): e00605-17
Dvorin JD. Getting Your Head around Cerebral Malaria. Cell Host Microbe; 22(5): 586-8.
Kumar S, Kumar M, Ekka R, Dvorin JD, Paul AS, Madugundu AK, Gilberger T, Gowda H, Duraisingh MT, Prasad TSK, Sharma P. PfCDPK1 mediated signaling in erythrocytic stages of Plasmodium falciparum. Nature Communications; 8: 63 (2017).
Bei AK, Ahouidi AD, Dvorin JD, Miura K, Diouf A, Ndiaye D, Premji Z, Diakite M, Mboup S, Long CA, Duraisingh MT. Functional analysis reveals geographical variation in inhibitory immune responses against a polymorphic malaria antigen. The Journal of Infectious Diseases (2017).
Ganter M, Goldberg JM, Dvorin JD, Paulo JA, King JG, Tripathi AK, Paul AS, Yang J, Coppens I, Jiang RHY, Elsworth B, Baker DA, Dinglasan, Gygi SP, Duraisingh MT. Plasmodium falciparum CRK4 directs continous rounds of DNA replication during schizogony. Nature Microbiology (2017).
2016
Absalon S, Robbins JA, Dvorin JD.
An essential malaria protein defines the architecture of blood-stage and transmission-stage parasites. Nature Communications, 2016;7:11449
Blomqvist K, DiPetrillo C, Streva, VA, Pine S, Dvorin JD.
2015
Sun M, Li W, Blomqvist K, Das S, Hashem Y, Dvorin JD, Frank J.
Dynamical features of the Plasmodium falciparum ribosome during translation. Nucleic Acids Research 2015;43(21):10515-24
2014
Raj DK, Nixon CP, Nixon CE, Dvorin JD, DiPetrillo CG, Pond-Tor S, Wu HW, Jolly G, Pischel L, Lu A, Michelow IC, Cheng L, Conteh S, McDonald EA, Absalon S, Holte SE, Friedman JF, Fried M, Duffy PE, Kurtis JD. Antibodies to PfSEA-1 block parasite egress from RBCs and protect against malaria infection. Science 2014; 344(6186):871-7
Dvorin JD. Inside scoop on outside proteins. Infection and Immunity 2014; 82(3):921-3
2012
Farrell A*, Thirugnanam S*, Lorestani A*, Dvorin JD*, Eidell KP, Ferguson DJP, Anderson-White BR, Duraisingh MT, Marth GT, Gubbels M-J. A DOC2 Protein Identified by Mutational Profiling is Essential for Apicomplexan Parasite Exocytosis. Science, 2012; 335(6065): 218-21.
* Co-first authors
2010
Dvorin JD, Martyn DC, Patel SD, Grimley JS, Collins CR, Hopp CS, Bright AT, Westenberger S, Winzeler E, Blackman MJ, Baker DA, Wandless TJ, Duraisingh MT. A plant-like kinase in Plasmodium falciparum regulates parasite egress from erythrocytes. Science 2010; 328(5980): 910-912.
Dvorin JD, Bei AK, Coleman BI, Duraisingh MT. Functional diversification between two related Plasmodium falciparum merozoite invasion ligands is determined by changes in the cytoplasmic domain. Molecular Microbiology 2010; 75(4): 990-1006.
Pre-2010
Bushkin GG, Ratner DM, Cui J, Banerjee S, Duraisingh M, Jennings C, Dvorin JD, Gubbels MJ, Robertson S, Steffen M, O’Keefe BR, Robbins PW, Samuleson J. Suggestive evidence for Darwinian selection against asparagine-linked glycans of Plasmodium and Toxoplasma. Eukaryotic Cell 2009; 9(2): 228-241.
Dong C, Patel V, Yang JC, Dvorin JD, Duraisingh MT, Clardy J, Wirth DF. Type II NADH dehydrogenase of the respiratory chain ofPlasmodium falciparum and its inhibitors. Bioorganic & Medicinal Chemistry Letters 2009; 19: 972-975.
Patel V, Booker M, Kramer M, Ross L, Celatka CA, Kennedy LM, Dvorin JD, Duraisingh MT, Sliz P, Wirth DF, Clardy J. Identification and characterization of small molecule inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase. Journal of Biological Chemistry 2008; 283(50): 35078-35085.
Estivariz CF, Park SY, Hageman JC, Dvorin JD, Melish MM, Arpon R, Coon P, Slavish S, Kim M, McDougal LK, Jensen B, McAllister S, Lonsway D, Killgore G, Effler PE, Jernigan DB. Emergence of community-associated methicillin resistant Staphylococcus aureus in Hawaii, 2001-2003. Journal of Infection 2007; 54: 349-357.
Dvorin JD, Bell P, Maul GG, Yamashita M, Emerman M, Malim MH. Reassessment of the roles of integrase and the central DNA flap in human immunodeficiency virus type 1 nuclear import. Journal of Virology 2002; 76(23): 12087-12096.
Bouyac-Bertoia M*, Dvorin JD*, Fouchier RAM, Jenkins J, Meyer BE, Wu LI, Emerman M, Malim MH. HIV-1 infection requires a functional integrase NLS. Molecular Cell 2001; 7: 1025-1035.
* Co-first authors
Fultz PN, Vance PJ, Endres MJ, Tao B, Dvorin JD, Davis IC, Lifson JD, Montefiori DC, Marsh M, Malim MH, Hoxie JA. In vivo attenuation of simian immunodeficiency virus by disruption of a tyrosine-dependent sorting signal in the envelope glycoprotein cytoplasmic tail. Journal of Virology 2001; 75(1): 278-291.